• GPCRs, G-proteins, effectors and their interactions: human-gpDB, a database employing visualization tools and data integration techniques 

      Satagopam, V. P.; Theodoropoulou, M. C.; Stampolakis, C. K.; Pavlopoulos, G. A.; Papandreou, N. C.; Bagos, P. G.; Schneider, R.; Hamodrakas, S. J. (2010)
      G-protein coupled receptors (GPCRs) are a major family of membrane receptors in eukaryotic cells. They play a crucial role in the communication of a cell with the environment. Ligands bind to GPCRs on the outside of the ...
    • Interpreting the Omics 'era' Data 

      Pavlopoulos, G. A.; Iacucci, E.; Iliopoulos, I.; Bagos, P. (2013)
      The analysis and the interpretation of the complex and dynamic biological systems has become a major bottleneck nowadays. The latest high-throughput "omics" approaches, such as genomics, proteomics and transcriptomics and ...
    • Using graph theory to analyze biological networks 

      Pavlopoulos, G. A.; Secrier, M.; Moschopoulos, C. N.; Soldatos, T. G.; Kossida, S.; Aerts, J.; Schneider, R.; Bagos, P. G. (2011)
      Understanding complex systems often requires a bottom-up analysis towards a systems biology approach. The need to investigate a system, not only as individual components but as a whole, emerges. This can be done by examining ...
    • Which clustering algorithm is better for predicting protein complexes? 

      Moschopoulos, C. N.; Pavlopoulos, G. A.; Iacucci, E.; Aerts, J.; Likothanassis, S.; Schneider, R.; Kossida, S. (2011)
      Background: Protein-Protein interactions (PPI) play a key role in determining the outcome of most cellular processes. The correct identification and characterization of protein interactions and the networks, which they ...